CD31 anticorps (PE)
Aperçu rapide pour CD31 anticorps (PE) (ABIN6297663)
Antigène
Voir toutes CD31 (PECAM1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Mouse anti-Human PECAM-1 Antibody [Sodium Azide Free]
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Specificité
- Cell surface and cytoplasm of endothelial cells
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Purification
- Stimulated human leukocytes (Workshop VI) were used as the immunogen for the PECAM-1 antibody.
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Immunogène
- Stimulated human leukocytes (Workshop VI) were used as the immunogen for the PECAM-1 antibody.
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Indications d'application
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Western blot: 2-4 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
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Autre désignation
- Platelet endothelial cell adhesion molecule
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Sujet
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Target Description: CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 mAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Gene Symbol: PECAM1
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ID gène
- 5175
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UniProt
- P16284
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Pathways
- Regulation of Actin Filament Polymerization
Antigène
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